EdenteV2, Main, Exploration, bibRecord, 000840

Evaluation of bone morphogenic proteins in periodontal practice

Identifieur interne : 000840 ( Main/Exploration ); précédent : 000839; suivant : 000841

Evaluation of bone morphogenic proteins in periodontal practice

Auteurs : Supreet Kaur ; Vishakha Grover ; Harkiran Kaur ; Ranjan Malhotra

Source :

Indian Journal of Dentistry [ 0975-962X ] ; 2016.

RBID : PMC:4836095

Abstract

Forty years ago Marshal R. Urist discovered a substance in bone matrix that had inductive properties for the development of bone and cartilage, until date, at least 20 bone morphogenetic proteins (BMPs) have been identified, some of which have been shown in vitro to stimulate the process of stem cell differentiation into osteoblasts in human and animal models. The purpose of this paper is to give a brief overview of BMPs and to review critically the clinical data currently available on the use of BMPs in various periodontal applications. The literature on BMPs was reviewed. A comprehensive search was designed. The articles were independently screened for eligibility. Articles with authentic controls and proper randomization and pertaining specifically to their role in periodontal applications were included. The available literature was analyzed and compiled. The analysis indicates BMPs to be a promising, as well as an effective novel approach to reconstruct and engineer the periodontal apparatus. Here, we represent several articles, as well as recent texts that make up a special and an in-depth review on the subject. On the basis of the data provided in the studies that were reviewed BMPs provide revolutionary therapies in periodontal practice.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836095

DOI: 10.4103/0975-962X.179379
PubMed: 27134452
PubMed Central: 4836095

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>Forty years ago Marshal R. Urist discovered a substance in bone matrix that had inductive properties for the development of bone and cartilage, until date, at least 20 bone morphogenetic proteins (BMPs) have been identified, some of which have been shown <italic>in vitro</italic>
 to stimulate the process of stem cell differentiation into osteoblasts in human and animal models. The purpose of this paper is to give a brief overview of BMPs and to review critically the clinical data currently available on the use of BMPs in various periodontal applications. The literature on BMPs was reviewed. A comprehensive search was designed. The articles were independently screened for eligibility. Articles with authentic controls and proper randomization and pertaining specifically to their role in periodontal applications were included. The available literature was analyzed and compiled. The analysis indicates BMPs to be a promising, as well as an effective novel approach to reconstruct and engineer the periodontal apparatus. Here, we represent several articles, as well as recent texts that make up a special and an in-depth review on the subject. On the basis of the data provided in the studies that were reviewed BMPs provide revolutionary therapies in periodontal practice.</p>
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Serveur d'exploration sur le patient édenté

Evaluation of bone morphogenic proteins in periodontal practice

Evaluation of bone morphogenic proteins in periodontal practice

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	Serveur d'exploration sur le patient édenté
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